Alexandre Giguère

• Quantum chemistry
• Theoretical and Computational chemistry

• Molecular Electronic Devices
• Machine Learning
• Modeling and artificial intelligence
• Climate security
• Deep Uncertainty

Alexandre Giguère is an assistant professor of Chemistry at the Royal Military College of Saint-Jean since 2023. He holds a M. Sc. in Medicinal Chemistry and a Ph. D. in Theoretical Chemistry from University of Montreal. His research interest focuses on the application of machine learning to molecular electronic devices discoveries. He is also interested in merging deep learning and decision making under deep uncertainty in climate security, notably as part of a project led by Bruno Charbonneau (RMC Saint-Jean).

He co-organized the Leadersphere 2025 Conference, "Turbulence: Canada in the midst of the climate crisis", co-hosted by Royal Military College Saint-Jean and the NATO Centre of Excellence on Climate Change and Security (CCASCOE).

Scientific Papers (peer-reviewed)

• Charbonneau, B. and Giguère, A. The Polycrisis and the Uncertainty Possibility Space, Global Sustanaibility, Cambridge Press (submitted and accepted).
• Giguère, A.; Ernzerhof, M. (2021). Extending the source-sink potential method to include electron-nucleus coupling, Journal of Chemical Physics, 155 (1), 014110.
• Ernzerhof, M.; Giguère, A.; Mayou, D. (2020). Non-Hermitian Quantum Mechanics and Exceptional Points in Molecular Electronics. Journal of Chemical Physics, 152 (24), 244119.
• Giguère, A.; Ernzerhof, M.; Mayou, D. (2018). Surface Plasmon Polariton-Controlled, Molecular Switch. Journal of Physical Chemistry C, 122, 35, p. 20083-20089.
• Hanessian, S.; Giguère, A.; Grzyb, J.; Maianti, J.P; Saavedra, M. O; Aggen, J. B.; Linsell, M.S.; Goldblum, A.A; Hildebrandt, D. J.; Kane, T. R; Dozzo, P; Gliedt, M. J.; Rowena D. M; Feeney L. A; Amstrong, E. S. (2011). Toward Overcoming Staphylococcus aureus Aminoglcyoside Resistance Mechanisms with a Functionally Designed Neomycin Analogue. Medicinal Chemistry Letters, 2 (12), p. 924–928.
• Hanessian, S.; Pachamuthu, K.; Szychowski J.; Giguère, A.; Swayze, E.; Migawa M.; François, B.; Kondo, J.; Westhof E. (2010). Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: a synergistic hydrophobic effect against resistant bacteria Bioorg, Chem. Med. Lett. (20), p. 7097-7101.

Refereed Conferences

• Charbonneau, B. and Giguère, A. (2024). Panel 3: ‘’Expertise and Knowledge Gaps’’, Climate Security and its Challenges Conference, April 8, Université du Québec à Montréal, Montreal, Canada.
• Charbonneau, B.; Giguère, A.; Baudu, P. (2023). Scenario-building, AI, and Decision-making in the Artic under Climate Change, Climate Change and Security, October 3-5, Lerici, Italy.
• Charbonneau, B.; Giguère, A.; Fletcher, K.; Russo, A.; Osler, J. (2023). Panel 2: Climate Change and Security Education, Climate Change and Security, October 3-5, Lerici, Italy.
• Giguère, A.; Maianti, J.P.; Gryzb, J.; Hanessian, S. (2009). Vers l’antibiotique de l’avenir - aminoglycosides semi-synthétiques de nouvelle génération – Groupe de recherche universitaire sur le médicament (GRUM), September 24-25, Université de Montréal, Montreal, Canada.

Poster Presentations

• Charbonneau, B. and Giguère, A. (2023). Interdisciplinary Talent Generation for Climate Governance and Security: a program overview from Canada, Climate Change and Security, October 3-5; Lerici, Italy.
• Giguère, A. and Ernzerhof, M. (2022). Extending the source-sink potential method to include electron-nucleus coupling, WATOC 2020: 12^th Triennial Congress of the World Association of Theoretical and Computational Chemists, July 3-9, Vancouver, Canada.
• Giguère, A.; Ernzerhof, M.; Mayou, D. (2019). Surface Plasmon Polartion-Controlled Molecular Switch, Canadian Symposia on Theoretical and Computational Chemistry, July 15-19, Windsor, Canada.
• Kövesi,I., Giguère, A., Laberge, M. (2013). Role of Conformational Dynamics in Mammalian Peroxidase Function, 57^th Annual Conference of the Biophysical society, February 2-6, Philadelphia, USA.
• Giguère, A., Kövesi, I., Laberge, M. (2013). Modelling Mammalian Peroxidases. 57^th Annual Conference of the Biophysical society; February 2-6, Philadelphia, USA.

• Aggen, J. B.; Linsell, M.; Goldblum, A. A.; Hildebrandt, D. J.; Kane, T.; Dozzo, P.; Gliedt, M. J.; Hanessian, S.; Giguère, A.; Grzyb, J.; Maianti, J.P. International Patent WO, 2010/030704 A2
• Maianti, J.P.; Aggen, J.; Dozzo, P; Linsell, M.; Goldblum, A.; Hanessian, S.; Giguère, A.; Gryzb, J. International Patent WO 2011/044498

• Development of new undergraduate programs in Geopolitics and Climate Security
• Head of the Science department (2024-2020)
• Acting President of the Faculty and Pedagogical Assembly (2022-2018)

2017

• Marian Olynyk Award
  

  Exceptional contributions to the Academic Wing, Royal Military College Saint-Jean

2012

• Class of '65 Teaching Excellence Award
  

  Excellence in teaching, Royal Military College Saint-Jean

• 2023 - Canadian Association of Theoretical Chemists
• 2023 - Research group – Climate Security, Centre for security and crisis governance (CRITIC), Royal Military College Saint-Jean
• 2023 - System Analysis and studies panel of NATO on Climate Security (SAS 182).

• Canadian Defence Academy Research Programme grant (CDARP), 2023-2026
• Co-PI, Insight Grant, SSHRC, project ‘’Intervention and the Transformation of Sahelian States in the Context of Violent Extremism’’ (2019-2023), PI: Bruno Charbonneau
• Collaborator, project ‘’Foresight: Planning for Low-Carbon Warfare’’ (2025), NATO Chief Scientist Grants Programme, PI: Bruno Charbonneau